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Poor Performance: Significant capacity reduction at higher C-rates
Synthetic DSIP was reported to cross the blood-brain barrier in early transport assays, supporting the idea that a peripherally administered compound could reach central targets
Functional studies in zebrafish have provided in vivo evidence that disruption of Pgrmc1 (progesterone receptor membrane component 1)a membrane-associated protein that physically interacts with CYP51A1leads to cataract formation, likely due to impaired CYP51A1 activity and dysregulated cholesterol metabolism [48]
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