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While this combination can be effective for short-term weight loss, phentermine has significant limitations: it is typically only approved for short-term use (12 weeks), it can raise blood pressure and heart rate, it carries abuse potential, and it does not improve blood sugar or insulin sensitivity

The most commonly reported adverse effects of GLP-1-based therapies are gastrointestinal in nature

Some people benefit from staying at each dose for 6 to 8 weeks before increasing, especially if they experience side effects that take time to resolve

This affects how fast semaglutide works when incorporated into our program