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Furthermore, the peptide component enhances cellular communication, signaling melanocytes to reduce overproduction of melanin while simultaneously promoting the repair of damaged skin structures that may perpetuate pigmentation problems

In addition, combination therapies represent a particularly promising avenue for maximising the efficacy of ferroptosis-based interventions

Two hundred ng of DNA was denatured and bisulfite converted at 95 C for 20 min, followed by methylation-specific real-time PCR using three pairs of primers designed with MethPrimer that targeted the CpG islands in the SOX2 promoter region (Table S1)

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