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AOD9604 is a synthetic fragment of human growth hormone designed to influence fat metabolism, whereas GLP1 medications like Semaglutide act on gut and brain hormone pathways to reduce appetite and improve blood sugar

EPP is the primary approved clinical indication for Afamelanotide and has generated the most extensive translational research programme characterising MT-1s photoprotection mechanisms in human subjects

Animal and pre-clinical evidence, limited human surgical data

For pilot studies or budget-constrained projects where oral administration isn't a factor, the acetate salt remains a viable and economical choice