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The investigators conducted a chart review of health records from a single medical center to identify patients with a BMI of at least 27 who were prescribed either semaglutide (which is sold under the brand name Wegovy when used for weight management) or the dual GLP-1RA and glucose-dependent insulinotropic polypeptide receptor agonist tirzepatide (Mounjaro
BMJ, 392
doi: 10.1371/journal.pbio.3000097 72 SymeCAZhangLBiselloA
(2000) demonstrated that the GHK-Cu complex directly stimulated MMP-2 expression (gelatinase A) in fibroblast cultures, while other research documented differential effects on collagenolytic activity
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