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In a clinical trial of semaglutide injection for weight loss (Wegovy) in patients with T2DM and a BMI of 27 kg/m2 or more, hypoglycemia (defined as a plasma glucose less than 54 mg/dL) was reported in 6.2% of semaglutide-treated patients versus 2.5% of placebo-treated patients
It works through two receptors: GLP-1 suppresses appetite and slows digestion, and GIP supports insulin sensitivity and metabolic efficiency
Some people report feeling more energized within a few days of their first shot
Higher doses are subject to the regulations for Therapeutic Use Exemptions (TUE)
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