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On the other hand, treatment of cancer cells with the anti-IGF-IR mAb cixutumumab paradoxically triggers cancer cells to produce IGF2, which in turn recruits macrophages and fibroblasts to promote angiogenesis and metastasis thereby hampering the efficacy of cixutumumab [190]

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Neuroscience Letters, 583, 81-87

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Biochemical genetics of glutathione-S-transferase in man

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Hursting: Theres a constellation of metabolic changes that occur with obesity

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