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What is in GHK-Cu Pimple Patches
AOD-9604 is a modified fragment of human growth hormone (hGH), derived from the C-terminal region commonly described as hGH 176191 (sometimes written as Tyr-hGH 177191)
Advantage: Convenient, familiar, non-invasive Challenge: Peptides face proteolytic degradation in the stomach and small intestine Bioavailability: Estimated at approximately 38% based on comparative pharmacology (see below) Transdermal (Patch) Some researchers have explored transdermal patches to deliver peptides: Advantage: Avoids first-pass metabolism and GI degradation Challenge: Intact skin is a strong barrier to peptide penetration Feasibility: Not commonly available commercially
Volkow N, Fowler J, Wang G, Baler R, Telang F
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