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In individuals with obesity and diabetes, the incretin effect is diminished, contributing to poor glucose tolerance
Use lower BMI thresholds (usually reduced by 2.5 kg/m 2 ) for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family backgrounds
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Vision Changes Some people with diabetes have reported worsening diabetic retinopathy when starting GLP-1 medications, possibly related to rapid blood sugar improvement
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