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The pancreas generally continues to secrete enzymes normally, and the small intestine maintains its absorptive capacity

If low-dose trials plateau after 8-12 weeks without hunger reduction, structured escalation to intermediate doses typically unlocks further weight loss

The study found that Body weight and body composition were maintained one year after termination of supervised exercise, in contrast to weight regain after termination of treatment with obesity pharmacotherapy alone. Dr Winnett recommends encouraging your patients to just get moving: at least 30 minutes of exercise per day, five times per week, including ideally two or three sessions of weight-bearing exercise a week. 6

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