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Indeed, GLP-1RA therapy appears to be well tolerated overall, and proportions of clinical trial participants discontinuing treatment because of adverse events tend to be low (5.49.9%) [10, 37, 39, 43, 46, 47]

The primary endpoint, major adverse cardiovascular events (MACE), was the time to first occurrence of a three-part composite outcome which included CV death, non-fatal myocardial infarction (MI) and non-fatal stroke

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