oasis 1 trial semaglutide The first GLP-1 weight-loss pill: what the 4 found Filip K. Knop on Twitter

Hydration and Electrolytes With less food intake and occasional nausea or gastrointestinal side effects, dehydration can develop quickly when taking semaglutide

severe or persistent upper abdominal pain should prompt urgent medical assessment [10] [11] Dehydration and acute kidney injury (AKI): gastrointestinal fluid losses can lead to dehydration, which may precipitate AKI, particularly in those with pre-existing renal impairment or those taking nephrotoxic medicines Delayed gastric emptying: this may affect the absorption of orally administered medicines, including contraceptive pills and thyroid replacement therapy [11] Injection site reactions: redness, bruising, or discomfort at the subcutaneous injection site Heart rate changes: increases in resting heart rate have been noted with GLP-1 class agents [14] [15] Hypoglycaemia: particularly if used alongside insulin or sulphonylureas Potential pancreatitis risk: a class concern with GLP-1 receptor agonists

If night sweats occur during treatment, other causes should be thoroughly investigated

Who is a good candidate for these treatments