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Neurological investigations showed raised plasma homocysteine and methylmalonic acid towards the upper limit of normal with a low serum vitamin B12 MRI showed an extensive cord lesion in keeping with subacute combined degeneration of the spinal cord

These properties are relevant given the established role of HGH in cartilage growth and repair through the local stimulation of IGF-1

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With vitamin C , the concern applies mainly to pure L-ascorbic acid, which is used at a low, acidic pH