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However, Chu found that activation of p53 alone did not significantly downregulate GSH/GSSG ratio, glutathione levels, and GPX4 activity in human cancer cells
A recent study provided a new perspective on mitochondrial glutamine metabolism, offering mechanistic insights into metabolic adaptation during tumor hypoxia, the emergence of drug resistance, and glutaminolysis-induced metabolic reprogramming and presenting metabolic strategies to target glutamine metabolism in cancer cells
Russo, G
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