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Overall agreement 90%: A+ 65%, A 25%, A 5%, D 0%, D 5%, D+ 0%
The PA criteria require BMI 30 or higher (or 27 with a comorbidity such as type 2 diabetes, hypertension, dyslipidemia, OSA, or CVD), documentation of a 6-month structured weight management program, prescriber attestation that lifestyle change alone has failed, and age 18 or older
Clinically, GLP-1 medicines are used to help regulate appetite and reduce energy intake, which supports weight loss when paired with diet and activity changes
Samples that underwent molecular profiling and/or sequential multiplex were collected by the Nervous System Tumor Bank (NSTB) under an additional IRB-approved protocol
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