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These stories underline a key point: managing weight and blood sugar plays a crucial role in maintaining and improving heart health

Rizzo agreed that the association of NAION with a drug that is anti-inflammatory, neuroprotective and vasculoprotective is problematic, noting that at present there is no substantive basis for explaining the link between semaglutide and NAION

For semaglutide specifically, patients with kidney dysfunction do not require renal dosing adjustments (Key Considerations in Use of SGLT2 Inhibitors and GLP-1RAs for CV Risk Reduction in Patients with T2D, 2020) Contraindications to GLP-1 agonists include a history of serious hypersensitivity reactions to a GLP-1 agonist, pregnancy, breastfeeding, and a personal or family history of medullary or thyroid cancer or MEN2 (Key Considerations in Use of SGLT2 Inhibitors and GLP-1RAs for CV Risk Reduction in Patients with T2D, 2020)

It applies to any GLP-1 medication, not just Ozempic