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The trial enrolled adults with overweight or obesity and randomised them to receive CagriSema, cagrilintide alone, semaglutide alone, or placebo over 32 weeks
Using complex CRC GEMMs with proficient immune signalling, we demonstrate an increase in cell death and survival in these heterogeneous tumours, more akin to a tumour histology than xenograft or PDX counterparts 21,78
One of the ways it does this is by transporting fat to mitochondria where it can be burned as a source of energy