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Guideline for perioperative care for people with diabetes mellitus undergoing elective and emergency surgery

Sci Signal 2012

Its involvement in fatty acid metabolism may help support healthy lipid metabolism and energy production in heart tissue

A few years after these publications, a competing hypothesis was proposed, suggesting that the formation of reactive oxygen species (ROS) during the metabolism of APAP by cytochrome P450 enzymes results in extensive lipid peroxidation (LPO), which is responsible for cell death [11,12]