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Similarly, both lixisenatide 163 and dulaglutide 160 administration led to positive changes in different paradigms of depression induced in mice

That cross-substance signal points to a shared biology underlying addiction, and it opens the door to a fundamentally different approach: not treating one addiction at a time, but targeting that common biologic signal, that common craving across addictions

Mood and Motivation: Some individuals find that boosting neurotrophic factors correlates with better mood regulation and a heightened sense of motivation or mental clarity