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Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR mutant lung cancer
The involvement of some B-complex vitamins in selenomethionine and selenocysteine pathways is the same as their involvement in corresponding sulfur pathways, because animal metabolism does not distinguish between sulfur and selenium amino acid analogs
Both systems depend on NADPH as their primary electron donor, making NADPH a central metabolic link between antioxidant mechanisms and overall cellular pathways
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