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This dose aligns with a large portion of the clinical literature, allows users to match many common study protocols, and makes it easier to increase intake gradually if a higher dose is warranted

As it does not appear to be harmful, l-carnitine is commonly recommended in severe VPA poisoning, especially in children, although the clinical benefit in terms of liver protection or hastening of recovery from unconsciousness has not been established clearly

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Differences in instruments, observation windows, and study populations may further contribute to inconsistency