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In fact, people with diabetes are twice as likely to have heart disease or stroke.[2] The leading cause of morbidity and mortality for individuals with diabetes is atherosclerortic cardiovascular disease (CVD), which includes coronary heart disease, cerebrovascular disease or peripheral arterial disease

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When you combine thicker bile with a gallbladder thats not emptying well, you start seeing more gallbladder attacks. A meta-analysis of 76 randomized clinical trials found that the risk of gallbladder problems increases when weight-loss medications are used at higher doses and for longer durations