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Concern was initially raised by the findings of the SUSTAIN-6 CVOT that suggested the risk of DR complications was elevated in patients using semaglutide compared with placebo (3.0% vs 1.8%, P = .02)

When using hotel refrigerators, patients should place the pen away from the freezer compartment and check that the refrigerator temperature is appropriatesome hotel mini-fridges run too cold

When Side Effects Are Not Normal Most symptoms are expected, but a few situations require medical evaluation

This metabolic stability becomes one of the appreciated side benefits of treatment, even for those primarily focused on weight loss