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Possible Long-Term Considerations Some early studies suggest that prolonged or repeated use may cause desensitization of the melanocortin system
Sexually transmitted infections (STIs): Some STIslike gonorrhea, chlamydia, and herpescan cause inflammation and bleeding in the rectum
This piece in 1993 also provided new insights into the biology of exendin, namely that exendin-4 was a full agonist of the human GLP-1 receptor, which Mojsov argues was crucial to convincing Amylin to develop exendin as a drug for diabetes (see below)
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