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We also used propensity score to match study groups on predefined characteristics, emulating participants randomizations using predefined stratifications criteria The study groups included: (1) GLP1-RA group: patients who initiated GLP1-RA, and (2) active comparator group, consisted of patients who initiated DPP4i, both initiated after meeting eGFR entry criteria

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For instance, FOXO4-D-Retro-Inverso (DRI) induces the selective apoptosis of senescent cells by inhibiting the FOXO4-p53 interaction 34