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As we age or experience chronic stress, this software can become corruptedpro-inflammatory genes may become overactive, while genes responsible for repair and antioxidant defense become suppressed
Since cholesterol levels in cells are tightly controlled (cholesterol is critical to many cellular functions), the shutdown of cellular cholesterol synthesis causes the cell to respond by increasing the activity of the LDL receptor on the cell surface, which has the net effect of pulling LDL particles out of the bloodstream and into the cell
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