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This article compares the two head-to-head on mechanism, evidence, safety, and access plus the upstream genetic variables that apply regardless of which compound a provider ultimately discusses
One well-documented interaction is with certain anti-epileptic drugs: high-dose pyridoxine may reduce the plasma levels of phenytoin and phenobarbital by enhancing their hepatic metabolism, potentially diminishing their anticonvulsant efficacy
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It is interesting to note that L-methionine was required at a concentration at least 10-fold higher than the other SAA, likely due to methionines roles in protein synthesis and direct incorporation into most proteins 21,22
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