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( a ) Schematic and representative images illustrating generation of 5FU resistant AKP organoids by continuous culture in increasing concentrations of drug, images at 4x magnification with mean organoid diameter denoted
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at the same 1:2000 as before), the c-met binding index was still higher than the control HGF ( bar 8 ) and the original LASSS/peroxynitrite-pretreated HGF (1:4000
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