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~ AlphaMD If you've been following the testosterone conversation at all, you probably know it's been a bit of a regulatory mess
To put that in perspective, the best semaglutide clinical trials showed approximately 15-17% weight reduction, and tirzepatide results peaked around 20-22%
Most studies use fixed doses, though you'll occasionally see weight-based protocols (110 mcg/kg, or roughly 0.54.5 mcg/lb) in the literature
Those flaws made it impossible to tell whether the improvement was due to placebo effects, because many injuries get better over time anyway, or from the peptides
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