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on 24 patients with generalized vitiligo and 20 healthy controls found statistically significant higher levels of superoxide dismutase activity in erythrocytes, serum MDA, and nitric oxide (NO) and statistically significant lower levels of glutathione and glutathione peroxidase in the patients of vitiligo compared to the controls.[] Secondary to the oxidative stress, the polyunsaturated fatty acids undergo peroxidation resulting in formation of free radicals

Long-term use of vitamin E has been shown to strengthen major blood vessels in diabetics

The first two Met-rich motifs and last Met-rich motif are located at the extracellular N terminus and the end of the second transmembrane structural domain, respectively

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