These drugs mimic the action of glucagon-like peptide-1 (GLP-1), a naturally occurring hormone in the body that plays a key role in regulating blood sugar levels, satiety, and digestion
While the study was observational (meaning that causality cant be confirmed), it does add to the growing body of evidence suggesting that its worth investigating these weight-loss drugs as potential cancer prevention tools, says lead author, Professor Elizabeth McDonald
25,26,27 We first performed RNA-seq of wild-type PGCs at E9.5 and analyzed the FPKM values of TRIM family genes (Supplementary information, Table S1)
A meta-analysis showed no statistically significant difference in efficacy between the two formulations at week 26, despite the numerically higher HbA1c response and body weight with sc semaglutide [59, 60]