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They are particularly beneficial for individuals experiencing insulin resistance, a common condition that hinders weight loss and can lead to fatigue and sugar cravings
Understanding the pharmacological profile of these drugs helps contextualise any symptoms that arise during treatment, including concerns about swollen lymph nodes, which warrant careful clinical evaluation to determine their underlying cause
The meta-analysis by Tuersun found no significant difference in body weight reduction when comparing the combination therapy to either GLP-1RA monotherapy or SGLT2i monotherapy: this finding challenges the assumption of a synergistic or additive effect on weight loss [15]
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