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B12 deficiencies are usually a result of diet, especially among vegans, this is because we can only get vitamin b12 through foods such as meat, fish and dairy products, our bodies do not produce it
For observational studies reporting serum vitamin B12 levels, the certainty of evidence was upgraded from low to moderate due to the large and consistent magnitude of effect across studies, despite heterogeneity
Drug Discovery Today , 20 (1), 122128
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