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Current understanding is largely based on pharmacovigilance data, clinical trial secondary endpoints, case reports, and small observational studies
It is not FDA-approved for weight loss, but may be prescribed off-label for this purpose
This genetic "re-programming" essentially directs skin cells to behave younger, enhancing resilience and elasticity
[40] These results, published in the New England Journal of Medicine in 2009, showed that EPP patient's "tolerance to artificial light and melanin density increased significantly by day 120 after the start of afamelanotide, to 11 times and 1.3 times the baseline values"
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