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Feature Medication Type FDA-approved Active ingredient Average weight loss Price Wegovy Pen Once weekly Yes Semaglutide 15% in a year* Starts at $199 Wegovy Pill Once daily Yes Semaglutide 14% in a year* Starts at $149 Two ways to take Wegovy Same active ingredient

Its most advanced use, the CagriSema combination, has produced late-stage trial data but remains under regulatory review

The dimethiconol containing silicone blends leave a silky smooth, non-greasy film on the skin

Some people look for early day-to-day improvements in 48 weeks, while more noticeable consistency with activity can take closer to 812 weeks