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We have to look at patients holistically, who have kidney disease and diabetes, to address the totality of risks, certainly progression to kidney failure, but also prevention of cardiovascular events and deaths. Ozempic and other GLP-1s will be compared to another diabetes drug class, SGLT-2 inhibitors Given Ozempics reduction of kidney disease events in the FLOW study, it seems likely that the GLP-1s will be used together with and compared against SGLT-2 inhibitor drugs
The goal of scientific investigation is to understand these differences rather than assuming that one approach is automatically superior to another
Its receptors, found in the pancreas, stomach, kidney, heart, lungs, skin, immune cells, and hypothalamus, stimulate insulin release, slow stomach emptying, inhibit post-meal glucagon release, and reduce food intake
