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Always adhere to recommended dosages and consult with a healthcare professional for personalized guidance

Most information comes from patient forums and social media, where reports are mixed: some describe renewed appetite suppression on re-start, while others report weight gain during breaks and significant nausea on resuming previous doses, often requiring a full re-titration

Risk of bias tools - ROBINS-I V2 tool Accessed 16 Aug 2025 Schnemann HJ, Brennan S, Akl EA et al (2023) The development methods of official GRADE articles and requirements for claiming the use of GRADE - a statement by the GRADE guidance group

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