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They include exenatide, from the Gila monster ( Heloderma suspectum ), and human GLP-1 analogs, such as liraglutide and semaglutide
Improving Metabolic Health: GLP-1 therapies enhance insulin sensitivity and glucose metabolism, which are critical for preventing age-related metabolic disorders such as diabetes and obesity (Mller et al., 2019)
When combined with TAM, it exhibits a significant synergistic inhibitory effect on MCF-7 and T-47D cell growth ( Z-Ligustilide, a phthalate compound, is the primary active ingredient of the Chinese herbal medicine Angelica sinensis (Oliv.) Diels
The frequent onset of acute dose-dependent kidney injury, with the potential of leading to long-term renal damage, has limited its use and hampered adequate dosing regimens, increasing the risk of suboptimal plasma concentrations during treatment
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