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Thus, it is not surprising that GSH (or the [GSH]/[GSSG] ratio) plays a key role in many diseases including cancer, inflammation, Alzheimer's disease, Parkinson's disease, sickle cell anemia, liver disease, cystic fibrosis, AIDS, heart attack, stroke, and diabetes [4, 6] as well as in aging [79]
Circulating MOTS-c levels are lower in older adults, lower in people with insulin resistance, and rise acutely in response to high-intensity exercise [2]
Understanding these risk factors can help you and your medical provider decide whether glutathione IV therapy is right for you
Inskeep PB et al
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