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First, the understanding of the mechanisms of insulin secretion regulation in pancreatic -cells has made significant progress, especially in recent years 40

In contrast, higher rates of early-onset PCO persist in patients implanted with silicone IOLs, with incidences ranging from 11% to 40.7% reported as early as 6 weeks to 3 months postoperatively ( Table 2 ) (107, 110, 126, 127), although advances in silicone IOL manufacturing have now led to the release of square-edged silicone IOLs with lower rates (90, 128)

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