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Many epidemiological investigations have reported an association between lower levels of vitamin B12 or folate (or elevated blood homocysteine and methylmalonic acid, which are metabolic indicators of vitamin B12 deficiency) and Alzheimer disease or other forms of cognitive impairment (57
In the absence of intrinsic factor (eg, from pernicious anemia or gastrectomy), the gut absorbs about 1% of ingested cobalamin, and this appears to be true even in patients with diseases of the ileum
AOD9604 (anti-obesity drug 9604) is a peptide linked to weight loss
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