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A particularly valuable direction for future research lies in characterizing the structureactivity relationships of these microbial metabolites and validating their efficacy in relevant disease models
& van Jansen, P
Oxidative stress and cardiovascular complications in type 2 diabetes: from pathophysiology to lifestyle modifications
(1998, JAMA) demonstrated in a placebo-controlled crossover study of 32 healthy older adults that 25 mg daily raised mean 24-hour GH concentration and IGF-1 significantly, with IGF-1 increases averaging roughly 40% above baseline
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