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We prioritized designed sequences with the smallest (first generation) and largest (third generation) distance from the training set
Efficacy is similar, though oral absorption requires strict dosing rules and higher amounts of the active drug
Likewise, for assessing the change in relative IBA1 or GFAP in the hippocampus or entire brain following semaglutide treatment, a linear model was constructed for each protein and each brain region using the protein percentage as dependent variable and treatment (veh-LPS and sema-LPS) and time (2d and 11d after the last LPS injection) as independent variables with interaction effects
Liu T, Zhong S, Liao X, Chen J, He T, Lai S, et al
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