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Pfizer discussed the case with the study site and internal and external hepatologists, as well as shared clinical details with regulators, including the FDA. The pharma company did not provide any additional details of the discussions with regulators
Further studies are needed to define the best Se-status biomarkers related to male fertility, their optimal ranges, analytical techniques for their assessment, and the optimal Se supplementation dosages, formulations, and treatment durations
For many clients, yes- especially when you hydrate well afterward and follow a solid skincare routine
At recommended doses, clinically meaningful hyperpigmentation is uncommon, around 1% in trials
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