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The October 2024 results: An average weight loss of 13.7% with Wegovy, compared with 3.2% on placebo 1 WOMAC pain score (0 to 100, higher is worse) dropped by 41.7 points with Wegovy versus 27.5 on placebo, a 14.1-point difference between the two groups 1 WOMAC physical function score dropped by 41.5 points versus 26.7 on placebo, a 14.9-point difference covering tasks like climbing stairs and getting up from a chair 1 The 14.1-point pain improvement is comfortably above the threshold most researchers use as the minimum patients actually feel in their day-to-day pain 1 STEP 9 is the first large trial to test a GLP-1 medication specifically in adults with osteoarthritis

For beneficiaries to be eligible under the BALANCE Model, providers must attest that they meet certain clinical criteria, including qualifying for a GLP-1 for a currently covered use (such as type 2 diabetes, cardiovascular disease risk reduction, or sleep apnea) or for use to treat obesity based on similar clinical criteria as applied in the Medicare GLP-1 Bridge (Figure 3)

Both medications can lead to side effects if not paired with proper food choices