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Long-acting GLP-1RAs can also improve the inflammatory response by regulating leptin levels in adipose tissue, which is beneficial for treating obesity-associated diseases [76]
However, in early animal studies, some GLP-1 drugs were associated with thyroid C-cell tumors
EPP is a rare photodermatosis caused by ferrochelatase deficiency , producing phototoxic protoporphyrin IX accumulation in erythrocytes and skin that causes severe pain and burning on exposure to visible light
These guidelines, while a starting point, are often based on a one-size-fits-all model (e.g., 8 or 12-weekly injections) that does not work for all patients
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