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Conservative protocol for beginners Goal: Assess tolerance and response before committing to full dosing Week 1: 50 mcg once daily (before bed, fasted) Week 2: 100 mcg once daily (before bed, fasted) Week 3-4: 100 mcg twice daily (morning and bedtime, both fasted) Week 5 onward: 100 mcg three times daily (if tolerated) This graduated approach allows researchers to assess their individual response to the appetite stimulation and any cortisol or prolactin-related effects before committing to full dosing
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The duration for which a patient remains on Ozempic varies and is determined on an individual basis, guided by the healthcare providers assessment of its suitability and effectiveness for the patients condition
The Surmount-5 trial had 25% and 30% weight loss reported, and max tolerated dose of tirzepatide caused 36% and 22% of patient hitting those two marks respectively
