Any other effect can be considered as a pleiotropic, off-target effect, or in the case of unwanted actions, adverse effects ( Figure 1 )
Prescription medication requiring medical supervision Contraindicated in patients with personal or family history of medullary thyroid carcinoma or MEN2 Most common adverse events are gastrointestinal (nausea, diarrhea, vomiting) Dose escalation schedule important to minimize GI side effects Efficacy and Safety of the Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide in Patients With Type 2 Diabetes (SURPASS-1): A Double-Blind, Randomised, Phase 3 Trial , published in The Lancet (Rosenstock J et al., 2021
According to the American Academy of Dermatology (AAD), sunscreen can help prevent sunburn, premature signs of aging, and skin cancer (when used in combination with other sun protection measures)
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