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If spray achieves even 20 to 40 percent of the absorbed dose of injection (a rough analogy from other peptide nasal delivery literature, not a BPC 157-specific number), the effective dose delivered may be far below what rodent studies used

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Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society , 11 (5), 266272

Glucagon-like peptide-1 (GLP-1) receptor agonists are a family of antihyperglycemic drugs that have demonstrated potent HbA1c reduction, low risk of hypoglycemia, with associated weight reduction, and proven cardiovascular and renal benefits.24 In this review we describe this type of drugs, their cardiovascular and renal benefits, as well as their clinical potential in patients with DKD, especially with the new oral semaglutide formulation, now available on the market