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White MF (2003) Insulin signaling in health and disease
Its HDAC inhibitory activity directly contributes to the reactivation of silenced tumor suppressor genes and is a key mechanism underlying its remarkable anti-tumor effects in urologic and other cancers, as observed both in vitro and in vivo without significant toxicity (64)
A phase I safety study in healthy adults confirmed that subcutaneous MOTS-c injections at doses up to 10 mg produced no serious adverse events, with a pharmacokinetic profile supporting once-daily or every-other-day dosing [3]
Resveratrol, a polyphenol from grapes, exhibits anti-inflammatory and tissue-protective properties that are beneficial for bladder health
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